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天然产物

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重组蛋白

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Cat. No. Product Name Target Signaling Pathways
TJS1779 Protosappanin A

原苏木素A,PTA

NADPH-oxidase; IL Receptor; IκB/IKK; TNF; NF-κB; TLR; ROS; COX; HIV Protease; JAK; NO Synthase; STAT Angiogenesis; Apoptosis; Chromatin/Epigenetic; Immunology/Inflammation; JAK/STAT signaling; Microbiology/Virology; Neuroscience; NF-κB; Proteases/Proteasome; Stem Cells
Protosappanin A (PTA) 是从苏木中分离得到的免疫抑制成分和主要联苯化合物,通过下调 JAK2和 STAT3的磷酸化,抑制 JAK2/STAT3依赖的炎症通路。

天然产物

Protosappanin A
Cat.No: TJS1779
Synonym: 原苏木素A,PTA
Target: NADPH-oxidase, IL Receptor, IκB/IKK, TNF, NF-κB, TLR, ROS, COX, HIV Protease, JAK, NO Synthase, STAT
Cat. No. Product Name Species Expression System
TMPK-01271 Coagulation factor XI Protein, Cynomolgus, Recombinant (His)

F11,PTA,FXI,Coagulation factor

Cynomolgus HEK293 Cells
Factor XI (FXI) is the zymogen of a plasma protease (FXIa) that contributes to hemostasis by activating factor IX (FIX). In the original cascade model of coagulation, FXI is converted to FXIa by factor XIIa (FXIIa), a component, along with prekallikrein and high-molecular-weight kininogen (HK), of the plasma kallikrein-kinin system (KKS).
TMPY-01104 Coagulation factor XI/F11 Protein, Human, Recombinant (His)

coagulation factor 11,coagulation...

Human HEK293 Cells
Factor XI (plasma thromboplastin antecedent) is a plasma glycoprotein, and a zymogen acting as a serine protease which participates in blood coagulation as a catalyst in the conversion of factor IX to factor IXa in the presence of calcium ions. It is an unusual dimeric protease, with structural features that distinguish it from vitamin K-dependent coagulation proteases. The factor XI is synthesized in the liver as a single polypeptide chain with a molecular weight estimated between 125 ~160 kDa ...

重组蛋白

Coagulation factor XI Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPK-01271
Species: Cynomolgus
Expression System: HEK293 Cells
Coagulation factor XI/F11 Protein, Human, Recombinant (His)
Cat.No: TMPY-01104
Species: Human
Expression System: HEK293 Cells
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